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89,90 The ability of milk EVs to modulate various inflammatory pathways such as the TLR4-NF-B signaling cascade and NLRP3 inflammasome activation demonstrates their potential as therapeutics for inflammatory bowel disease (IBD) and necrotizing enterocolitis (NEC)

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A schematic diagram of the mechanism of ferroptosis in diabetic ulcers is shown in Figure 1

Recently, it was found that the levels of key enzymes in glycolysis were significantly higher in NAFLD in parallel with enhanced glycolytic capacity in NAFLD patients

Treatment effect of bumetanide in children with autism spectrum disorder: A systematic review and meta-analysis

New biological entities are either in discovery and preclinical (three) or in Phase II (three), including HMI-115, a prolactin receptor monoclonal antibody and MT 2990, a monoclonal antibody targeting interleukin-33 to treat pain