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It can be seen that tanshinone IIA can regulate the number of fibroblasts in tendon cells and collagen in tissues, and also regulate the balance of oxidation and antioxidants in the damaged area, reduce the damage of oxidative stress to the extracellular matrix, and protect chondrocytes

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The cause of endolymphatic hydrops is unclear, and while all patients with Mnire disease have endolymphatic hydrops, not all patients with endolymphatic hydrops have Mnire disease, which has led to the suggestion of an array of possible causes including genetic predisposition, viral infection, and multiple other biochemical and immune factors