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Leveraging this technology, Zeng et al

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In chronic inflammatory conditions, the 2019 meta-analysis of nine RCTs supported the significant impacts of CoQ 10 supplementation on the modulation of pro-inflammatory signals, including TNF- and IL-6 [50]

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In this view grxA and trxC were incorporated into the regulon in order to reduce disulfide bonds created not by H 2 O 2 but by other disulfide-generating stressors