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Looking beyond GLP-1 and insulin as payloads (a molecule that increasingly appears to be a poor commercial candidate), 29 at least ten companies are working on device-based solutions to administer proteins and monoclonal antibodies orally and some technologies including the RaniPill have reached Phase I

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Given the heterogeneity of the included interventions, it is also important to consider how the degree of VR immersion and the specific cognitive content may have influenced the observed outcomes