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To determine whether other oncogenes phenocopied CCNE1, we overexpressed MYC, which increases KG abundance 20,21 (Extended Data Fig

Interview How enzyme chemistry is reshaping peptide drugs July 8, 2026 Peptide drugs can target complex proteins but often lack stability in the body

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Reduced acetyl-CoA levels decrease the carbon flow into the TCA cycle, subsequently lowering enzyme activity necessary for these reactions and reducing ATP synthesis (Paiva et al

Mutational spectrum, copy number changes, and outcome: results of a sequencing study of patients with newly diagnosed myeloma