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105 Kitazawa et al

Within these reactive species we find superoxide anion (O 2 ), hydroxyl radical ( OH), nitric oxide (NO ), as well as other species of non-free radicals such as hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HClO) and peroxynitrite (ONOO )

BioMed Pharmacother (2018) 97:166372

Furthermore, socioeconomic status is closely associated with comorbidity risk, with lower-income, lower-educational attainment, and unemployed individuals demonstrating an increased susceptibility to chronic constipation and depression comorbidity (Howell et al., 2004)