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the intensity of the response, over time, will be less

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Additionally, compared to Pnldc1 single knockouts, Pnldc1::Henmt1 double knockout animals have more severe symptoms, such as smaller testicles and noticeable spermatogenic abnormalities [453, 458]

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instead, cells undergoing ferroptosis are characterized by a decrease in mitochondrial volume and crest and an increase in mitochondrial membrane density (32, 33)