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Someone with borderline high blood pressure might experience a more noticeable decrease than someone whose blood pressure is already optimal

The inflammatory phase begins immediately after injury, bringing immune cells to clear debris and release signaling molecules

doi:10.1126/sciadv.abo5284 317

Primary cells are another option which have much higher TEER and lower permeability than the available cell lines, but they are more time consuming, expensive, and can be passaged a limited number of times

Similarly, complete tendon ruptures where the tissue has fully separated usually require surgical repair regardless of peptide use