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DZN administered at 4.1 mg/kg to mice for 4 weeks increased testosterone levels, but it reduced testosterone levels when administered at 8.2 mg/kg [13]

Glutathione s-transferases

This approach reduces toxicity while preserving, or even enhancing, the original therapeutic effects to the greatest extent possible

10.1016/j.freeradbiomed.2025.09.049 103 LyuC.XiaoH.YinX.LiZ.HanC.XuR

This approach has been successful in the testing and eventual Food and Drug Administration (FDA) clearance of substances with poor bioavailability (80)