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Therefore, it can be summarized that, dAGEs disrupt the integrity of the intestinal barrier, leading to an increased permeability that facilitated the entry of luminal antigens, digestion-resistant AGEs and pathogenic bacteria into the lamina propria and peripheral circulation

JP21K14467) and the Takeda Science Foundation

Clinical, Cosmetic and Investigational Dermatology, 15, 18531862

Deep hydration is achieved by combining hyaluronic acid, squalane, and beta-glucan, which create an invisible yet robust moisture barrier

Abe H, Ishioka M, Fujita Y, Umeno A, Yasunaga M, Sato A, Ohnishi S, Suzuki S, Ishida N, Shichiri M, Yoshida Y

Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells