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2022AW039)

Mice pretreated with 0.5 mg/kg ALP showed preference for the environment paired with low dose of MOR (2.5 mg/kg) when compared to SAL-treated controls 1 month after cessation of pretreatment, suggesting that repeated ALP induces changes that last into adulthood

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Similar morphological changes have been reported in callus cultures of Ammi visnaga 11 , Datura inoxia 18 , and Melissa officinalis 64

In turn, epigenetics is defined by changes in the genome, which do not involve changes in the DNA sequence but can result in differences in gene expression