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When iron metabolism is disordered or ATG expression is abnormal, iron autophagy mediated by NCOA4 can induce ferroptosis by degrading ferritin and inducing iron overload ( Hypoxia can also affect iron metabolism

In the full-length Ab DPcob, full occupancy of AdoCbl is observed in the absence of BV, but the binding of both chromophores simultaneously is diminished compared to the Sas Pcob (Fig

Supplementation with 500-1,000 mcg daily or regular monitoring of serum B12 levels is advisable for at-risk individuals

Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial

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