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Unlike GH injections, it preserves endogenous pulsatility and does not suppress the HPG axis. Smith et al., Journal of Clinical Endocrinology & Metabolism Originally developed to treat muscle wasting, osteoporosis, and growth hormone deficiency in elderly patients, MK-677 has shown benefits in: Increasing lean body mass Improving sleep architecture and REM cycles Enhancing tendon and joint healing Reducing recovery time and inflammation Improving skin elasticity and hair quality Importantly, MK-677 is not a SARM , anabolic steroid, or peptide

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Blood routine examination and biochemical parameters Fresh blood was collected by cardiac puncture when termination at postoperative 28 days