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Once aggregation begins, the individual peptide molecules are no longer available to bind receptors

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This makes it a candidate for oral or subcutaneous delivery depending on the goal

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Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with ENaC-overexpressing mice

For GzmB-GSDME-induced liposome leakage, 0.4 M recombinant human His-sumo-GSDME was preincubated with 0.15610 M MeCbl for 0.5 h before addition of 0.4 M recombinant GzmB for another 2 h at 37 C