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Our HTS process uniquely identified six new drugs acting as Wnt agonists, marking the first extensive investigation in the world with a focus on identifying treatments for hair loss and nail issues that could stimulate the Wnt/-catenin signaling pathway

Advanced disease models, including genetically stratified organoids, patient-derived iPSC lines, and age-appropriate 3D brain cultures, may offer more refined platforms to dissect these differences and identify compound-subtype associations (Sirkis et al., 2022)

Monosaccharide composition and NMR analysis revealed that the polysaccharide and its derivatives contained Fucp, Xylp, Manp, and GlcAp in a molar ratio of 0.9:1.0:3.2:1.2

3 Rationale for drug delivery system in Alzheimer's disease: targeting the bloodbrain barrier Drug delivery systems (DDS) offer several advantages highly relevant to AD, including protection of therapeutic agents from degradation, improved solubility of poorly water-soluble drugs, prolonged circulation time, and the ability to engineer surface properties for active targeting (Singh et al., 2024)

USA 106 , 1404614051 (2009)

The significance of SIRT5 expression on DCM-related myocardial injury