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Therefore the patient will be closely followed for development of RA

10 Limitations of the study This study is a narrative review, which entails several important limitations

Because mitochondria naturally produce free radicals during energy production, antioxidant systems like glutathione play an important role in helping maintain balance

These include: Antacids Metformin Oral contraceptives Methotrexate High-dose niacin Sulfa drugs (e.g., Bactrim) Nitrous oxide (laughing gas) Improving Your Health With an MTHFR Gene Mutation If you suspect your health issues are linked to an MTHFR mutation, here are practical steps to support your body: Optimise your diet Prioritise natural folate (leafy greens, avocado, legumes), choline (eggs, salmon, liver), and B12-rich foods (meat, fish, eggs)

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