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6-Paradol increased tyrosine hydroxylase immunoreactivity and rescued dopaminergic neurons in the nigrostriatal pathway

In contrast, hCiPSC-NSCs-treated animals (Fig

doi: 10.1186/1999-3110-55-7 52 FujikawaT.IshiharaH.LeachJ

Residues in this domain can be oxidized by heme, allowing the protein RANBP2-type and C3HC4-type zinc finger containing 1 [RBCK1, also known as heme-oxidized IRP2 ubiquitin ligase (HOIL-1)] to mark it for degradation in response to heme availability (Wallander et al., 2008)

doi: 10.1371/journal.pone.0173911 27 Bravo-FerrerI.CuarteroM

The blinding of subjects and researchers was reported in four studies (Reference Hashim, Anwar and El-Fatah22,Reference Nasr9,Reference Chandil, Pande and Sen27,Reference Gayatri, Kumar and Kumar28)