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That group also demonstrated a significant decrease in brain-derived neurotrophic factor, which is thought to play a key role in a variety of neuroplastic processes, including pain modulation/transduction, nociception, and hyperalgesia

Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

Considering that this amino acid is essential for central nervous system (CNS) function and development (46), its decline has been associated with severe neurological disorders (47, 48)