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Pulm Pharmacol Ther 22:3743

The activity of CAT in groups 1 and 2 was similar until day 15

I., Fujita, M., and Hasanuzzaman, M., Antioxidants (Basel) , 2021, vol

Curcumin: Curcumin was obtained from Central drug house private limited, Mumbai, India

The number of samples per group was determined to be 6 in order to have 80% power of detecting a mean 0.92-fold change in expression of mRNA [27]

The secondary objectives were to assess the pharmacokinetics (PK), pharmacodynamics (PD) (ability to reduce circulating uric acid) and immunogenicity of pegadricase after a single intravenous dose