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For instance, spherical nucleic acid (SNA used to dysregulate miRNA, i.e., miR92b target of RNA interference) encapsulated liposomal nanoparticles conjugated with brain targeting peptides, i.e., rabies virus glycoprotein (RVG, is a neurotropic viral peptide targeting nicotinic acetylcholine receptors expressed on the BCECs, neurons, and glioma cells) and apolipoprotein-E

With further research on bionanomaterials, lipid-hybrid cell-derived biomimetic functional materials will play an important role in the treatment of tumors

The challenges in assessing the efficacy of drugs are compounded by the need for careful patient selection and clinical stratification

Li and Chory 1997