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This seemingly minor change -- the addition of a single methyl group -- can influence copper binding geometry, peptide stability, skin penetration, and biological activity

doi: 10.3390/ijms21218387 42 AlimICaulfieldJTChenYSwarupVGeschwindDHIvanovaEet al

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The invasion and migration of stomach cancer cells, as well as their peritoneal, lung, and liver metastases, are markedly enhanced by overexpression of CST1

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