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Iodinated density gradient media In the early nineteen-sixties Arne Byum, who was working in Oslo on the fractionation of blood leukocytes, recognized that the derivatives of triiodobenzoic acid that were being synthesized as X-ray imaging agents (for human intravenous injection) would also make ideal density gradient media for mammalian cell fractionation

Total glutathione (GSH) levels are depleted in MYCdriven liver tumors, which is associated with reduced glutathione synthesis

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Short-term induction with endocrine agents sensitizes ER+ breast cancer cells to ferroptosis inducers, indicating a non-mutational sensitization mechanism

However, this susceptible redox center can also be attacked by oxidative species during oxidation reaction

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