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Gut microbiota is an important part of the brain-gut axis, and changes in the microbiota affect brain development and the interaction between the gut and brain [146]

Jan 2011;21(1):128-131

doi: 10.4049/jimmunol.173.5.3186 165 CourtemancheCHuangACElson-SchwabIKerryNNgBYAmesBN

Accumulating evidence suggests that cholesterol and its metabolic intermediates influence cancer progression and immune regulation by remodeling the tumor microenvironment (TME)

intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies