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Buff Up Your Knowledge: Why Muscle Mass is More Important Than You Think As we age, our bodies can turn into sneaky ninjas, swapping out muscle for less active fat

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long-term human data is limited

At the same time, direct evidence shows that fibroblast migration is modulated through extracellular vesicles derived from macrophages [153], as the vesicles carry a rich cargo of growth factors, cytokines, and microRNAs that can alter the inflammatory milieu, promote angiogenesis, and directly or indirectly stimulate fibroblast proliferation and activation [151,153,154]

Site rotation importance Repeatedly injecting in the same location can cause local tissue changes including lipohypertrophy (abnormal fat accumulation) or lipoatrophy (fat loss creating depressions)