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Gastric bypass surgery has been performed worldwide for over 30 years

Medications Some commonly prescribed drugs can reduce B12 levels: Metformin : Metformin treats type 2 diabetes and can cause B12 absorption problems, especially when taken long term

DAO is an enzyme found in the gut that metabolizes histamine in the GI tract, which can be a significant source of histamine, especially in the presence of SIBO, candida overgrowth and certain pathogenic infections like For more information you can read Thakkar, 2011 ) High levels of histamine in the body can impair sleep

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The good news is that options like b12 shots for hangovers can potentially help mitigate these symptoms by aiding in rehydration and nutrient replenishment