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If a patient is asking about GLP-1/GIP medicines, direct them to a conversation with their prescriber and share neutral background reading on those medicines from peer-reviewed journals

The Kraus 2014 study reported that adipocyte-specific NNMT knockdown in mice increased adipocyte energy expenditure through a mechanism interpreted as elevated methyl-donor availability for polyamine biosynthesis and for histone methylation that modulates adipocyte gene-expression programs [2]

The symptoms of B12 deficiency can be incredibly sneaky, often mimicking other conditions

Scientific References Frequently Asked Questions How quickly will I feel better after starting B12 injections

Does BST-1, a protein homologous to CD38, play a role in organismal NAD homeostasis

Symptoms of vitamin B12 deficiency Symptoms tend to develop slowly and may not be recognized immediately