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The plant glutathione peroxidase enzymes (GPXs) may be involved in the detoxification of H 2 O 2 and organic hydroperoxides and in the regulation of the cellular redox homeostasis by maintaining the thiol/disulfide balance

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FIGURE 4 IGF1 mediates therapy resistance in human cancers simply through the following steps: Firstly, radiotherapy increases the expression of IGF1 and IGF1R (Osuka and Van Meir, 2017)

Key spliceosomal snRNPsU1, U2, U4, U5 and U6play distinct roles: U1 snRNP binds to the 5SS, while U2 snRNP attaches to the branch point, crucial for the integration and activation of the spliceosome (Fig