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The reversal of these effects by the MG scavenger SC confirmed MGs central causative role

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The subsequent buildup of lipofuscin, characteristic of lysosomal aggregates, is associated with metabolic disruptions and impaired autophagic function, establishing it as a key biomarker for cellular aging 29

Not only does glutathione directly neutralize free radicals, but it also has the ability to regenerate other antioxidants, such as vitamins C and E, back to their active forms