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Notably, axons of MSNs are myelinated (Bishop et al., 1982), while dopaminergic neurons localized in the SNpc are scarcely myelinated despite having long axons (Sulzer and Surmeier, 2013

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The chemical stressor used for the empirical support, PQ, is a well-known substance with a toxicity primarily mediated by redox cycling (Day et al., 1999