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bEnd.3 cells from each treatment group were incubated at 37 C for 30 min in medium lacking FBS that contained 10 M DCHF-DA and then replaced with fresh medium with ionizable molecules at doses of 0.25 mg/mL (and incubated for 2 h) or 0.05 mg/mL (and incubated for 1 h, 4 h, 12 h or 24 h)

Phosphatidylserine at both 20 and 40 mg/kg significantly restored Akt phosphorylation, whereas restoration of mTOR phosphorylation reached statistical significance only at 40 mg/kg ( p = 0.13 for 20 mg/kg dose

United States Food and Drug Administration (US-FDA)

Eur Rev Med Pharmacol Sci (2020) 24(2):4918

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