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402 Currently, multiple clinical studies targeting Tregs have been initiated in T1D, including low-dose IL-2 administration and adoptive Treg transfer, both of which have shown some potential benefits

Hence, avoiding the use of harsh chaotropic or utilizing mild denaturing conditions for solubilization was the primary goal with the hope to obtain bioactive fusion protein

Marzi M, Zucchi A, Lombi R et al: Implant surgery in Peyronie's disease

Studies have demonstrated that humans are continuously exposed to MPs and NPs by inhalation or ingestion (46)

J Cell Biol 106: 761771