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Their main mechanisms include membrane disruption, wherein they interact with microbial membranes, integrating into the lipid bilayer and causing physical disruption, pore formation, or complete membrane disintegration

This resulted in the selection of leucovorin and dyclonine, two FDA-approved compounds, which we demonstrated to have brain repair and pro-oligodendrogenic activities in both preterm birth brain injury and adult demyelination mouse models, with leucovorin demonstrating broader beneficial effects

A phase 2 proof-of-concept trial for chronic obstructive pulmonary disease

Abnormal heart rhythms associated with high doses of Celexa (citalopram hydrobromide)

Facial expressions