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Interestingly, such changes in mitochondrial NADH/NAD + redox are directly affected by glutamate oxaloacetate transaminase 2 (GOT2), a mitochondrial enzyme whose activity also contributes to tryptophan catabolism 69,70 and amino acid metabolism 71

-Tocopherol demonstrates significant regulatory effects on free radicals and lipid peroxides in precancerous conditions (72)

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