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Paracetamol is one of the most commonly used analgesic and antipyretic drugs. Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N acetyl parabenzoquinone imine and its antidote, N acetyl l cysteine Scientific Reports Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram Mechanism of paracetamol induced hepatotoxicity Download Scientific Diagram A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Blog Archives
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