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Although, no proof for sulfenic acid formation was provided, the authors speculated that Cys511 of Cys511Cys535 disulfide first reacted with hydroxide ion to expel the Cys535 thiolate, which in turn, reacted with another disulfide to give disulfide scrambling

Smeyne M, Smeyne RJ

Glutathione S-transferase polymorphisms: influence on susceptibility to cancer

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New York: McGraw Hill Inc (1995)

Nuclear factor-kappa B (NF-B) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, and genes involved in cell proliferation, adhesion, survival, and differentiation