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6.3 Protein S-glutathiolation from GSNO As mentioned above, in addition to transnitrosation, GSNO can react slowly with thiols to form a disulfide resulting in S-glutathiolation

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doi: 10.1128/IAI.00014-21 Summary Keywords gut microbiota, immunomodulation, probiotics, targeted delivery, ulcerative colitis Citation Niu C, Wang J, Lu X and Yu Y (2026) Probiotics for ulcerative colitis: mechanisms, therapeutic advances, and emerging strategies

64 It is reported that bacteria can metabolize the chemotherapeutic drug gemcitabine (2,2-difluorodeoxycytidine) into its inactive form (2,2-difluorodeoxyuridine), which depends on the bacterial enzyme cytidine deaminase

This clinical trial history provides access to a published pharmacokinetic and safety dataset, including human tolerability data that is unusual for a research-stage metabolic peptide