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It is especially given to patients who are in the ICU or who require parenteral nutrition (nutrition through IV)

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Wu S-J, Tam K-W, Tsai Y-H, Chang C-C, Jane C-J, Chao (2010) Curcumin and Saikosaponin A Inhibit Chemical-Induced Liver Inflammation and Fibrosis in Rats

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Inform patients of the risk of life-threatening respiratory depression, including information that the risk is greatest when starting hydrocodone bitartrate and acetaminophen tablets or when the dosage is increased, and that it can occur even at recommended dosages