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As the unconventional XBP1 mRNA splicing by IRE1 and the subsequent activation of the spliced XBP1 protein expression are the major mechanism of ER homeostasis regulation by IRE1 10 , we tested whether XBP1 plays a role in IRE1-mediated ferroptosis sensitization

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For example, glutathione works in combination with almost all other antioxidants, so omitting them is essentially a case of going halfway