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It is important to note that the group treated with melatonin alone did not show any significant changes in the biomarkers listed above, compared to the control group, at the given dose of melatonin

In the presence of normal levels of ROS, the expression of Nrf2 is controlled by the Kelch-like ECH-associated protein 1 (Keap 1), which targets Nrf2 to ubiquitin-mediated degradation in the cytoplasm

This combination can contribute to maintaining a youthful and radiant appearance

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Lin et al., 2017), reduce airway smooth muscle tone (Lam et al., 2019), and combined with lung cancer-related airway structural abnormalities, significantly increase the risk of nighttime airway collapse, inducing or worsening OSA