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Efficacy of serine/glycine conversion inhibitor sertraline with radiotherapy was investigated by proliferation, clonogenic and spheroid assays, and in vivo using a serine/glycine dependent NSCLC mouse model by assessment of tumor growth, metabolite and cytokine levels, and immune signatures

Lr GUS crystals were formed by incubation of 5 mg/mL Lr GUS in 17% PEG3350, 0.4 M NaCl, and 0.1 Tris HCl pH 7.4 at 20 C

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DCA recommendations for IS patients in different regions Epidemiological evidence does not indicate a direct carcinogenic effect of DCA in humans, and long-term use of DCA has been shown to lack haematological, hepatic, or renal toxicity [17, 127]

Novel aspects of toxicity mechanisms of dioxins and related compounds