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Gebara E, Zanoletti O, Ghosal S, Grosse J, Schneider BL, Knott G, et al

When a patient is prescribed Ozempic for weight loss, it is considered an off-label prescription, which means that the prescription was written at the providers discretion using their medical expertise when determining that the medication was medically appropriate for the patients health condition, even when it was not FDA-approved for this condition

Thus, folate builds up in the form of 5mTHF (the "methyl trap") and there is less folate in the forms CH 2 -THF and 10f-THF that are the substrates for thymidylate and purine synthesis, respectively

They found that patients given 1000 micrograms (mcg) of vitamin B12 for a six-month period experienced a substantial decrease in break-outs or even a complete cure

Sharifi MR, Hassanpour H, Khajali F