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Behavioral profile of vitamin B(12) deficiency: a reflection of impaired brain development, neuronal stress and altered neuroplasticity

Research indicates that stimulation of monoaminergic neurotransmission can impact metabolic rate by increasing energy expenditure either directly through activation of peripheral 3 adrenergic receptors in brown adipose tissue (increasing thermogenesis) or indirectly through central dopamine receptor-dependent increases in motor activity

Two randomized controlled trials, three prospective papers, one systematic review, and three clinical reviews fulfilled inclusion criteria

In 2004, Ramaekers et al

NY Acad

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