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TSPO levels in the MFC also showed positive associations with napping frequency and sleep insufficiency, a convergent pattern consistent with the idea that insufficient sleep increases need for recovery, where greater napping behavior may be (i) a compensatory behavior for insufficient nocturnal sleep [58] (consistent with the MFC associations for shorter sleep, fatigue, and sleep insufficiency), and/or (ii) greater sleep need related to low-grade neuroinflammatory processes

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No such protection was observed in mice overexpressing GPX1 (Fig

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