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153 As a compensatory mechanism, IAPP may activate HIF-1/6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) to protect against oligomer toxicity, thus delaying the loss of cells but at the cost of impairing cell function

Rangan, J

We further evaluated whether the administration of mitapivat might synergize with the beneficial effect of splenectomy in 4.2 / mice

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