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NO, a gaseous signaling molecule, has emerged as a promising agent for modulating hypoxic microenvironments (Table 4)

Muscle Weakness Another common symptom of B12 deficiency is muscle weakness

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identified NCOA4 as the selective cargo receptor for the autophagic turnover of ferritin during ferroptosis, demonstrating that genetic inhibition of NCOA4 suppressed ferritin degradation and consequently inhibited Erastin-induced ferroptosis (54)