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Increased glutathione levels help maintain healthy nitric oxide levels, protecting it from damage and storing it for sustained use, which is particularly important in maintaining vascular health as well as supporting immune function

Vitamin B12 also may be involved in maintaining sulfhydryl (SH) groups in the reduced form required by many SH-activated enzyme systems

2 Erythrocytes are particularly vulnerable to oxidative stressors due to their role in oxygen transport, thus acute hemolytic anemia is the main associated pathology