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The antibacterial mechanism was found to involve the generation of ROS, which was confirmed by electron spin resonance with spin trapping

Notably, prevotella histicola from human gut microbiota suppressed the development of arthritis,but the exact mechanism of action is unclear

"Overexpression of the formaldehyde dehydrogenase gene from Brevibacillus brevis to enhance formaldehyde tolerance and detoxification of tobacco." Appl Biochem Biotechnol 169(1): 170-180

Further, unlike other glutathione peroxidases (GPx1, GPx2, GPx3, GPx5, and GPx6) which exist as homo(tetra)-oligomeric proteins, GPx4 is a monomeric protein of about 20 kDa and misses the tetramer interfaces for oligomer formation (Scheerer et al., 2007

To view a copy of this licence, visit About this article Cite this article Karako, E., Halal, S.O., Haneli, R.H