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doi: 10.1111/acel.12344

Zgheib NK, Sleiman F, Nasreddine L, Nasrallah M, Nakhoul N, Ismaeel H, Tamim H (2018) Short telomere length is associated with aging, central obesity, poor sleep and hypertension in Lebanese individuals

In the mitochondrial matrix, pyruvate dehydrogenase (PDH) generates acetyl-CoA using pyruvate, which initiates the TCA cycle, thereby producing reducing agents from carbohydrates (Figure 1)