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Targeting the cerebrovascular large neutral amino acid transporter (LAT1) isoform using a novel disulfide-based brain drug delivery system

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Indeed, we found male L-DKO mice to have a greater hepatocellular injury than female Gclc L-KO mice (Fig

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Endogenous IL-1 has been reported to be insufficient for activating and recruiting neutrophils, and even high pharmacological doses of IL-1 fail to exacerbate APAP-induced liver injury, indicating that IL-1 signaling is not a critical contributor to APAP-induced hepatotoxicity

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10.1177/1934578x1501000408 57 TheoharidesT

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