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In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal

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However, the discontinuation rates for Danuglipron across different doses were over 50%, significantly higher than the approximately 40% observed in the placebo group, indicating poor tolerability in some patients

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